| Description : |
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
89.8 kDa |
| AA Sequence : |
MMDGPRSDVGRWGGNPLQPPTTPSP EPEPEPDGRSRRGGGRSFWARCCGC CSCRNAADDDWGPEPSDSRGRGSSS GTRRPGSRGSDSRRPVSRGSGVNAA GDGTIREGMLVVNGVDLLSSRSDQN RREHHTDEYEYDELIVRRGQPFHML LLLSRTYESSDRITLELLIGNNPEV GKGTHVIIPVGKGGSGGWKAQVVKA SGQNLNLRVHTSPNAIIGKFQFTVR TQSDAGEFQLPFDPRNEIYILFNPW CPEDIVYVDHEDWRQEYVLNESGRI YYGTEAQIGERTWNYGQFDHGVLDA CLYILDRRGMPYGGRGDPVNVSRVI SAMVNSLDDNGVLIGNWSGDYSRGT NPSAWVGSVEILLSYLRTGYSVPYG QCWVFAGVTTTVLRCLGLATRTVTN FNSAHDTDTSLTMDIYFDENMKPLE HLNHDSVWNFHVWNDCWMKRPDLPS GFDGWQVVDATPQETSSGIFCCGPC SVESIKNGLVYMKYDTPFIFAEVNS DKVYWQRQDDGSFKIVYVEEKAIGT LIVTKAISSNMREDITYLYKHPEGS DAERKAVETAAAHGSKPNVYANRGS AEDVAMQVEAQDAVMGQDLMVSVML INHSSSRRTVKLHLYLSVTFYTGVS GTIFKETKKEVELAPGASDRVTMPV AYKEYRPHLVDQGAMLLNVSGHVKE SGQVLAKQHTFRLRTPDLSLTLLGA AVVGQECEVQIVFKNPLPVTLTNVV FRLEGSGLQRPKILNVGDIGGNETV TLRQSFVPVRPGPRQLIASLDSPQL SQVHGVIQVDVAPAPGDGGFFSDAG GDSHLGETIPMASRGGATRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
