Recombinant Human THG1L Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human THG1L Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : THG1L-5807H
Product Overview : THG1L MS Standard C13 and N15-labeled recombinant protein (NP_060342) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 34.8 kDa
AA Sequence : MWGACKVKVH DSLATISITL RRYLRLGATM AKSKFEYVRD FEADDTCLAH CWVVVRLDGR NFHRFAEKHN FAKPNDSRAL QLMTKCAQTV MEELEDIVIA YGQSDEYSFV FKRKTNWFKR RASKFMTHVA SQFASSYVFY WRDYFEDQPL LYPPGFDGRV VVYPSNQTLK DYLSWRQADC HINNLYNTVF WALIQQSGLT PVQAQGRLQG TLAADKNEIL FSEFNINYNN EPPMYRKGTV LIWQKVDEVM TKEIKLPTEM EGKKMAVTRT RTKPVPLHCD IIGDAFWKEH PEILDEDSTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : THG1L tRNA-histidine guanylyltransferase 1 like [ Homo sapiens (human) ]
Official Symbol : THG1L
Synonyms : THG1L; tRNA-histidine guanylyltransferase 1-like (S. cerevisiae); probable tRNA(His) guanylyltransferase; FLJ11601; FLJ20546; ICF45; interphase cytoplasmic foci protein 45;
Gene ID : 54974
mRNA Refseq : NM_017872
Protein Refseq : NP_060342
MIM : 618802
UniProt ID : Q9NWX6

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