Description : |
The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
78.8 kDa |
AA Sequence : |
MKPPAACAGDMADAASPCSVVNDLR WDLSAQQIEERTRELIEQTKRVYDQ VGTQEFEDVSYESTLKALADVEVTY TVQRNILDFPQHVSPSKDIRTASTE ADKKLSEFDVEMSMREDVYQRIVWL QEKVQKDSLRPEAARYLERLIKLGR RNGLHLPRETQENIKRIKKKLSLLC IDFNKNLNEDTTFLPFTLQELGGLP EDFLNSLEKMEDGKLKVTLKYPHYF PLLKKCHVPETRRKVEEAFNCRCKE ENCAILKELVTLRAQKSRLLGFHTH ADYVLEMNMAKTSQTVATFLDELAQ KLKPLGEQERAVILELKRAECERRG LPFDGRIRAWDMRYYMNQVEETRYC VDQNLLKEYFPVQVVTHGLLGIYQE LLGLAFHHEEGASAWHEDVRLYTAR DAASGEVVGKFYLDLYPREGKYGHA ACFGLQPGCLRQDGSRQIAIAAMVA NFTKPTADAPSLLQHDEVETYFHEF GHVMHQLCSQAEFAMFSGTHVERDF VEAPSQMLENWVWEQEPLLRMSRHY RTGSAVPRELLEKLIESRQANTGLF NLRQIVLAKVDQALHTQTDADPAEE YARLCQEILGVPATPGTNMPATFGH LAGGYDAQYYGYLWSEVYSMDMFHT RFKQEGVLNSKVGMDYRSCILRPGG SEDASAMLRRFLGRDPKQDAFLLSK GLQVGGCEPEPQVCSGPTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |