Recombinant Human THOP1 Protein, MYC/DDK-tagged

• Cat.No.: THOP1-888H
• Product Overview: Recombinant human THOP1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 78.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: thimet oligopeptidase 1[ Homo sapiens ]
• Official Symbol: THOP1
• Synonyms: EP24.15; MEPD_HUMAN; MP78; TOP
• Gene ID: 7064
• mRNA Refseq: NM_003249.3
• Protein Refseq: NP_003240
• MIM: 601117
• UniProt ID: P52888