Recombinant Human thyrotrophic embryonic factor, His-tagged
| Cat.No. : | TEF-216H |
| Product Overview : | TEF, 1-303aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
| Description : | Thyrotroph embryonic factor isoform 1, also known as TEF, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSH beta promoter. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by down-regulating beta chain expression of cytokine receptors. Recombinant human TEF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Source : | E.coli |
| Species : | Human |
| Tag : | His-tag |
| Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol |
| Molecular Mass : | 35.6kDa (326aa), confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher) |
| AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSDAGGG KKPPVDPQAG PGPGPGRAAG ERGLSGSFPL VLKKLMENPP REARLDKEKG KEKLEEDEAA AASTMAVSAS LMPPIWDKTI PYDGESFHLE YMDLDEFLLE NGIPASPTHL AHNLLLPVAE LEGKESASSS TASPPSSSTA IFQPSETVSS TESSLEKERE TPSPIDPNCV EVDVNFNPDP ADLVLSSVPG GELFNPRKHK FAEEDLKPQP MIKKAKKVFV PDEQKDEKYW TRRKKNNVAA KRSRDARRLK ENQITIRAAF LEKENTALRT EVAELRKEVG KCKTIVSKYE TKYGPL |
| Purity : | >85% by SDS - PAGE |
| Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| Concentration : | 0.25 mg/ml (determined by Bradford assay) |
| Gene Name : | TEF thyrotrophic embryonic factor [ Homo sapiens ] |
| Official Symbol : | TEF |
| Synonyms : | TEF; thyrotrophic embryonic factor; thyrotroph embryonic factor; KIAA1655; |
| Gene ID : | 7008 |
| mRNA Refseq : | NM_001145398 |
| Protein Refseq : | NP_001138870 |
| MIM : | 188595 |
| UniProt ID : | Q10587 |
| Chromosome Location : | 22q13.2 |
| Function : | double-stranded DNA binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; |
Products Types
| ◆ Recombinant Protein | ||
| TEF-9122M | Recombinant Mouse TEF Protein, His (Fc)-Avi-tagged | +Inquiry |
| TEF-5664R | Recombinant Rat TEF Protein, His (Fc)-Avi-tagged | +Inquiry |
| TEF-2757H | Recombinant Human TEF Protein, His-tagged | +Inquiry |
| TEF-4480R | Recombinant Rhesus Macaque TEF Protein, His (Fc)-Avi-tagged | +Inquiry |
| TEF-16629M | Recombinant Mouse TEF Protein | +Inquiry |
| ◆ Lysates | ||
| TEF-1152HCL | Recombinant Human TEF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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