"TLE1" Related Products

Recombinant Human TLE1 Protein, MYC/DDK-tagged

Cat.No.: TLE1-22H
Product Overview: Recombinant protein of human transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1) with C-MYC/DDK tag was expressed in HEK293T.
Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Source: HEK293T
Species: Human
Tag : MYC/DDK
Molecular Mass: 83 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage: Store at –80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration: >50 μg/mL as determined by microplate BCA method
Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name: TLE1
Official Symbol: TLE1 transducin like enhancer of split 1 [ Homo sapiens (human) ]
Synonyms: TLE1; transducin like enhancer of split 1; ESG; ESG1; GRG1; transducin-like enhancer protein 1; enhancer of split groucho-like protein 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
Gene ID: 7088
mRNA Refseq: NM_005077
Protein Refseq: NP_005068
MIM: 600189
UniProt ID: Q04724

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