"TLE1" Related Products

Recombinant Human TLE1 Protein, MYC/DDK-tagged

Cat.No. : TLE1-22H
Product Overview : Recombinant protein of human transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1) with C-MYC/DDK tag was expressed in HEK293T.
Description : Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Source : HEK293T
Species : Human
Molecular Mass : 83 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at –80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : TLE1
Official Symbol : TLE1 transducin like enhancer of split 1 [ Homo sapiens (human) ]
Synonyms : TLE1; transducin like enhancer of split 1; ESG; ESG1; GRG1; transducin-like enhancer protein 1; enhancer of split groucho-like protein 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
Gene ID : 7088
mRNA Refseq : NM_005077
Protein Refseq : NP_005068
MIM : 600189
UniProt ID : Q04724

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