| Description : |
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
86.7 kDa |
| AA Sequence : |
MSVQSSSGSLEGPPSWSQLSTSPTP GSAAAARSLLNHTPPSGRPREGAMD ELHSLDPRRQELLEARFTGVASGST GSTGSCSVGAKASTNNESSNHSFGS LGSLSDKESETPEKKQSESSRGRKR KAENQNESSQGKSIGGRGHKISDYF EYQGGNGSSPVRGIPPAIRSPQNSH SHSTPSSSVRPNSPSPTALAFGDHP IVQPKQLSFKIIQTDLTMLKLAALE SNKIQDLEKKEGRIDDLLRANCDLR RQIDEQQKLLEKYKERLNKCISMSK KLLIEKSTQEKLSSREKSMQDRLRL GHFTTVRHGASFTEQWTDGFAFQNL VKQQEWVNQQREDIERQRKLLAKRK PPTANNSQAPSTNSEPKQRKNKAVN GAENDPFVRPNLPQLLTLAEYHEQE EIFKLRLGHLKKEEAEIQAELERLE RVRNLHIRELKRINNEDNSQFKDHP TLNERYLLLHLLGRGGFSEVYKAFD LYEQRYAAVKIHQLNKSWRDEKKEN YHKHACREYRIHKELDHPRIVKLYD YFSLDTDTFCTVLEYCEGNDLDFYL KQHKLMSEKEARSIVMQIVNALRYL NEIKPPIIHYDLKPGNILLVDGTAC GEIKITDFGLSKIMDDDSYGVDGMD LTSQGAGTYWYLPPECFVVGKEPPK ISNKVDVWSVGVIFFQCLYGRKPFG HNQSQQDILQENTILKATEVQFPVK PVVSSEAKAFIRRCLAYRKEDRFDV HQLANDPYLLPHMRRSNSSGNLHMA GLTASPTPPSSSIITYSGPTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
