Recombinant Human TLR1 Protein (25-580 aa), His-tagged

• Cat.No.: TLR1-1815H
• Product Overview: Recombinant Human TLR1 Protein (25-580 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial.

Specification

• Description: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 65.2 kDa
• Protein length: 25-580 aa
• AA Sequence: SEFLVDRSKNGLIHVPKDLSQKTTI LNISQNYISELWTSDILSLSKLRIL IISHNRIQYLDISVFKFNQELEYLD LSHNKLVKISCHPTVNLKHLDLSFN AFDALPICKEFGNMSQLKFLGLSTT HLEKSSVLPIAHLNISKVLLVLGET YGEKEDPEGLQDFNTESLHIVFPTN KEFHFILDVSVKTVANLELSNIKCV LEDNKCSYFLSILAKLQTNPKLSNL TLNNIETTWNSFIRILQLVWHTTVW YFSISNVKLQGQLDFRDFDYSGTSL KALSIHQVVSDVFGFPQSYIYEIFS NMNIKNFTVSGTRMVHMLCPSKISP FLHLDFSNNLLTDTVFENCGHLTEL ETLILQMNQLKELSKIAEMTTQMKS LQQLDISQNSVSYDEKKGDCSWTKS LLSLNMSSNILTDTIFRCLPPRIKV LDLHSNKIKSIPKQVVKLEALQELN VAFNSLTDLPGCGSFSSLSVLIIDH NSVSHPSADFFQSCQKMRSIKAGDN PFQCTCELGEFVKNIDQVSSEVLEG WPDSYKCDYPESYRGTLLKDFHMSE LSCNIT
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: TLR1 toll-like receptor 1 [ Homo sapiens ]
• Official Symbol: TLR1
• Synonyms: TLR1; CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; MGC104956; MGC126311; MGC126312; DKFZp547I0610; DKFZp564I0682
• Gene ID: 7096
• mRNA Refseq: NM_003263
• Protein Refseq: NP_003254
• MIM: 601194
• UniProt ID: Q15399