Recombinant Human TLR5 protein, Fc-tagged
Cat.No. : | TLR5-392H |
Product Overview : | Recombinant Human TLR5(aa 21-639) fused with Fc region of human IgG1 at N-terminal was expressed in CHO cells. |
- Specification
- Gene Information
- Related Products
Source : | CHO |
Species : | Human |
Tag : | Fc |
Form : | 0.2 µm filtered solution in phosphate buffer with glycine, saccharose and stabilizing agents |
Molecular Mass : | Has an apparent molecular weight of 110 kDa on SDS-PAGE. |
Applications : | Neutralization, receptor binding assays |
Storage : | Store lyophilized product at -20 centigrade. Product is stable for at least 1 year. |
Gene Name : | TLR5 toll-like receptor 5 [ Homo sapiens ] |
Official Symbol : | TLR5 |
Synonyms : | TLR5; toll-like receptor 5; FLJ10052; MGC126430; MGC126431; SLEB1; TIL3; Toll/interleukin 1 receptor like protein 3; toll/interleukin-1 receptor-like protein 3; |
Gene ID : | 7100 |
mRNA Refseq : | NM_003268 |
Protein Refseq : | NP_003259 |
MIM : | 603031 |
UniProt ID : | O60602 |
Chromosome Location : | 1q32.3-q42 |
Pathway : | Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; Pathogenic Escherichia coli infection, conserved biosystem; |
Function : | interleukin-1 receptor binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
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TLR5-902H | Recombinant Human TLR5 protein, MYC/DDK-tagged | +Inquiry |
Tlr5-392M | Active Recombinant Mouse Tlr5 protein, Fc-tagged | +Inquiry |
TLR5-903H | Recombinant Human TLR5 protein, His-tagged | +Inquiry |
◆ Lysates | ||
TLR5-1045HCL | Recombinant Human TLR5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTLR5 helps regulate gut microbiota composition, maintaining intestinal health and preventing dysbiosis.
TLR5 plays a crucial role in protecting against gut bacterial infections by recognizing flagellin and initiating immune defense.
Dysfunctional TLR5 can contribute to inflammatory bowel diseases, affecting gut inflammation and immune responses.
TLR5 modulates inflammation, influencing cytokine production and the body's response to infection.
TLR5 detects bacterial flagellin, triggering signaling pathways that activate immune responses against infections.
Variations in TLR5 function can alter susceptibility to gastrointestinal infections and related disorders.
TLR5 is involved in developing systemic immunity, enhancing the body's overall defense against pathogens.
Customer Reviews (3)
Write a reviewOutstanding protein-protein interaction studies, vital for our experiments.
Accurate protein structural analysis, a cornerstone of our investigations.
High-quality protein characterization, fundamental for our research.
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