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Recombinant Human TMEM173 protein, His-tagged

Cat.No. : TMEM173-3282H
Product Overview : Recombinant Human TMEM173(174-379aa) fused with His tag at N-terminal was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : His
Form : Protein lyophilized in sterile PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, 300 mM Imidazole, pH 8.0). Trehalose (5-8%) and mannitol (5-8%) protectants were added before lyophilization.
Protein length : 174-379aa
AA Sequence : ELQARIRTYNQHYNNLLRGAVSQRL YILLPLDCGVPDNLSMADPNIRFLD KLPQQTGDHAGIKDRVYSNSIYELL ENGQRAGTCVLEYATPLQTLFAMSQ YSQAGFSREDRLEQAKLFCRTLEDI LADAPESQNNCRLIAYQEPADDSSF SLSQEVLRHLRQEEKEEVTVGSLKT SAVPSTSTMSQEPELLISGMEKPLP LRTDFS
Purity : > 80%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Store for up to 12 months at -20 centigrade to -80 centigrade as lyophilized powder.Storage of Reconstituted Protein:Short-term storage: Store at 2-8 centigrade for two weeks.Long-term storage: Aliquot and store at -20 centigrade to -80 centigrade for up to 6 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage (see Stability and Storage for more details).If a different concentration is needed for your purposes please adjust the reconstitution volume as required (please note: the ion concentration of the final solution will vary according to the volume used).Note: Centrifuge vial before opening. When reconstituting, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution.
Shipping : The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature (see below).
Gene Name : TMEM173 transmembrane protein 173 [ Homo sapiens ]
Official Symbol : TMEM173
Synonyms : TMEM173; transmembrane protein 173; FLJ38577; NET23; hMITA; hSTING; mediator of IRF3 activation; endoplasmic reticulum IFN stimulator; stimulator of interferon genes protein; mitochondrial mediator of IRF3 activation; endoplasmic reticulum interferon stimulator; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; ERIS; MITA; MPYS; STING;
Gene ID : 340061
mRNA Refseq : NM_198282
Protein Refseq : NP_938023
MIM : 612374
UniProt ID : Q86WV6
Chromosome Location : 5q31.2
Pathway : Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem;
Function : protein binding; protein homodimerization activity; protein kinase binding; protein kinase binding; transcription factor binding; ubiquitin protein ligase binding;

Products Types

◆ Recombinant Protein
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TMEM173-5854H Recombinant Human TMEM173 Protein (full-length), N-His tagged +Inquiry
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Tmem173-1437M Recombinant Mouse Tmem173 protein, His-tagged +Inquiry

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◆ Lysates
TMEM173-988HCL Recombinant Human TMEM173 293 Cell Lysate +Inquiry

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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