Recombinant Human TMEM173 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human TMEM173 Protein, Myc/DDK-tagged, C13 and N15-labeled

TMEM173 Related Products

Human(6)
Mouse(2)
Rat(1)
Zebrafish(1)

GST(1)
His(5)
His|T7(1)
Myc/DDK(1)
Myc|DDK(1)
N/A(1)

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Specification Gene Information Related Products

Cat.No. :	TMEM173-3290H
Product Overview :	TMEM173 MS Standard C13 and N15-labeled recombinant protein (NP_938023) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	42.2 kDa
AA Sequence :	MPHSSLHPSI PCPRGHGAQK AALVLLSACL VTLWGLGEPP EHTLRYLVLH LASLQLGLLL NGVCSLAEEL RHIHSRYRGS YWRTVRACLG CPLRRGALLL LSIYFYYSLP NAVGPPFTWM LALLGLSQAL NILLGLKGLA PAEISAVCEK GNFNVAHGLA WSYYIGYLRL ILPELQARIR TYNQHYNNLL RGAVSQRLYI LLPLDCGVPD NLSMADPNIR FLDKLPQQTG DHAGIKDRVY SNSIYELLEN GQRAGTCVLE YATPLQTLFA MSQYSQAGFS REDRLEQAKL FCRTLEDILA DAPESQNNCR LIAYQEPADD SSFSLSQEVL RHLRQEEKEE VTVGSLKTSA VPSTSTMSQE PELLISGMEK PLPLRTDFST RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	TMEM173 transmembrane protein 173 [ Homo sapiens (human) ]
Official Symbol :	TMEM173
Synonyms :	TMEM173; transmembrane protein 173; FLJ38577; NET23; hMITA; hSTING; mediator of IRF3 activation; endoplasmic reticulum IFN stimulator; stimulator of interferon genes protein; mitochondrial mediator of IRF3 activation; endoplasmic reticulum interferon stimulator; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; ERIS; MITA; MPYS; STING;
Gene ID :	340061
mRNA Refseq :	NM_198282
Protein Refseq :	NP_938023
MIM :	612374
UniProt ID :	Q86WV6