Recombinant Human TMX4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TMX4-6563H
• Product Overview: TMX4 MS Standard C13 and N15-labeled recombinant protein (NP_066979) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 38.8 kDa
• AA Sequence: MAGGRCGPQLTALLAAWIAAVAATA GPEEAALPPEQSRVQPMTASNWTLV MEGEWMLKFYAPWCPSCQQTDSEWE AFAKNGEILQISVGKVDVIQEPGLS GRFFVTTLPAFFHAKDGIFRRYRGP GIFEDLQNYILEKKWQSVEPLTGWK SPASLTMSGMAGLFSISGKIWHLHN YFTVTLGIPAWCSYVFFVIATLVFG LFMGLVLVVISECFYVPLPRHLSER SEQNRRSEEAHRAEQLQDAEEEKDD SNEEENKDSLVDDEEEKEDLGDEDE AEEEEEEDNLAAGVDEERSEANDQG PPGEDGVTREEVEPEEAEEGISEQP CPADTEVVEDSLRQRKSQHADKGLT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TMX4 thioredoxin-related transmembrane protein 4 [ Homo sapiens (human) ]
• Official Symbol: TMX4
• Synonyms: TMX4; thioredoxin-related transmembrane protein 4; thioredoxin domain containing 13, TXNDC13; DJ971N18.2; KIAA1162; PDIA14; protein disulfide isomerase family A; member 14; thioredoxin domain containing 13; thioredoxin domain-containing protein 13; protein disulfide isomerase family A, member 14; TXNDC13
• Gene ID: 56255
• mRNA Refseq: NM_021156
• Protein Refseq: NP_066979
• MIM: 616766
• UniProt ID: Q9H1E5