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Recombinant Human TNF Protein, His-tagged
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| Cat.No. : | TNF-001H |
| Product Overview : | Recombinant Human TNF Protein (77-233 aa (partial, without signal peptide)) with 6xHis tag was expressed in E. coli. |
| Description : | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Molecular Mass : | 18.4 kDa |
| Protein length : | 77-233 |
| Purity : | >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-TNFa (WB). |
| Applications : | ELISA, Western Blot, Antibody Production, Protein array |
| Quality Control Test : | 15% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-TNFa (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry. |
| Storage : | Prior to reconstitution, store the lyophilized protein at 2−8 centigrade. After reconstitution, store in working aliquots at −80 centigrade. |
| Expiry : | All components are stable for 1 year of receipt, if stored properly. |
| Storage Buffer : | 20mM Sodium Phosphate, 0.5M NaCl, pH 7.4. No preservatives added. |
| Shipping : | Lyophilized at Ambient temperature |
| Figure : |
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| Gene Name : | TNF tumor necrosis factor [ Homo sapiens (human) ] |
| Official Symbol : | TNF |
| Synonyms : | TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; cachectin; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha |
| Gene ID : | 7124 |
| mRNA Refseq : | NM_000594 |
| Protein Refseq : | NP_000585 |
| MIM : | 191160 |
| UniProt ID : | P01375 |
◆ Recombinant Protein
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| TNF-63H | Recombinant Human TNF Protein, FLAG-tagged | +Inquiry |
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◆ Lysates
| TNF-897HCL | Recombinant Human TNF 293 Cell Lysate | +Inquiry |
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