Recombinant Human TNF Protein, His-tagged
Cat.No. : | TNF-001H |
Product Overview : | Recombinant Human TNF Protein (77-233 aa (partial, without signal peptide)) with 6xHis tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 18.4 kDa |
Protein length : | 77-233 |
Purity : | >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-TNFa (WB). |
Applications : | ELISA, Western Blot, Antibody Production, Protein array |
Quality Control Test : | 15% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-TNFa (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry. |
Storage : | Prior to reconstitution, store the lyophilized protein at 2−8 centigrade. After reconstitution, store in working aliquots at −80 centigrade. |
Expiry : | All components are stable for 1 year of receipt, if stored properly. |
Storage Buffer : | 20mM Sodium Phosphate, 0.5M NaCl, pH 7.4. No preservatives added. |
Shipping : | Lyophilized at Ambient temperature |
Gene Name : | TNF tumor necrosis factor [ Homo sapiens (human) ] |
Official Symbol : | TNF |
Synonyms : | TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; cachectin; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha |
Gene ID : | 7124 |
mRNA Refseq : | NM_000594 |
Protein Refseq : | NP_000585 |
MIM : | 191160 |
UniProt ID : | P01375 |
Products Types
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TNF-2001H | Recombinant Human TNF Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TNF-897HCL | Recombinant Human TNF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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