Recombinant Human TNFRSF11A Protein, His-tagged

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Recombinant Human TNFRSF11A Protein, His-tagged

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Cat.No. : TNFRSF11A-151H
Product Overview : Recombinant Human TNF receptor superfamily member 11A(TNFRSF11A) protein, transcript variant 1(NM_003839), with a His tag, was expressed in human cells.
Description : The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Source : Human Cells
Species : Human
Tag : His
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.44, without any preservatives.
Molecular Mass : 19.3 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator [ Homo sapiens ]
Official Symbol : TNFRSF11A
Synonyms : TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, activator of NFKB; tumor necrosis factor receptor superfamily member 11A; CD265; RANK; receptor activator of NF-KB; osteoclast differentiation factor receptor; receptor activator of nuclear factor-kappa B; loss of heterozygosity, 18, chromosomal region 1; FEO; OFE; ODFR; OSTS; PDB2; OPTB7; TRANCER; LOH18CR1;
Gene ID : 8792
mRNA Refseq : NM_003839
Protein Refseq : NP_003830
MIM : 603499
UniProt ID : Q9Y6Q6
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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