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Recombinant Human TNFRSF25 Protein, Fc-tagged

Cat.No. : TNFRSF25-205H
Product Overview : Recombinant human TNFRSF25 protein with Fc tag was expressed in HEK293.
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Description : The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized
Molecular Mass : 45.5 kDa
Protein length : 417
AA Sequence : MEQRPRGCAAVAAALLLVLLGARAQ GGTRSPRCDCAGDFHKKIGLFCCRG CPAGHYLKAPCTEPCGNSTCLVCPQ DTFLAWENHHNSECARCQACDEQAS QVALENCSAVADTRCGCKPGWFVEC QVSQCVSSSPFYCQPCLDCGALHRH TRLLCSRRDTDCGTCLPGFYEHGDG CVSCPTSTLGSCPERCAAVCGWRQM FWVQVLLAGLVVPLLLGATLTYTYR HCWPHKPLVTADEAGMEALTPPPAT HLSPLDSAHTLLAPPDSSEKICTVQ LVGNSWTPGYPETQEALCPQVTWSW DQLPSRALGPAAAPTLSPESPAGSP AMMLQPGPQLYDVMDAVPARRWKEF VRTLGLREAEIEAVEVEIGRFRDQQ YEMLKRWRQQQPAGLGAVYAALERM GLDGCVEDLRSRLQRGP
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : TNFRSF25 tumor necrosis factor receptor superfamily, member 25 [ Homo sapiens (human) ]
Official Symbol : TNFRSF25
Synonyms : TNFRSF25; tumor necrosis factor receptor superfamily, member 25; TNFRSF12, tumor necrosis factor receptor superfamily, member 12 (translocating chain association membrane protein); tumor necrosis factor receptor superfamily member 25; APO 3; DDR3; DR3; LARD; TR3; TRAMP; WSL 1; WSL LR; protein WSL-1; death receptor beta; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; death domain receptor 3 soluble form; lymphocyte-associated receptor of death; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); APO-3; WSL-1; WSL-LR; TNFRSF12;
Gene ID : 8718
mRNA Refseq : NM_001039664
Protein Refseq : NP_001034753
MIM : 603366
UniProt ID : Q93038

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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