Active Recombinant Human TNFRSF4 Protein, hIgG/His-tagged
Cat.No. : | TNFRSF4-05H |
Product Overview : | Recombinant human TNFRSF4 (29-214aa), fused to hIgG-His-tag at C terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Source : | Insect cell |
Species : | Human |
Tag : | hIgG/His |
Form : | Liquid |
Bio-activity : | Measured by its binding ability in a functional ELISA with mouse OX40 Ligand/TNFSF4. The ED50 range ≤ 0.15 μg/mL. |
Molecular Mass : | 46.9 KDa (425aa) |
AA Sequence : | LHCVGDTYPSNDRCCHECRPGNGMV SRCSRSQNTVCRPCGPGFYNDVVSS KPCKPCTWCNLRSGSERKQLCTATQ DTVCRCRAGTQPLDSYKPGVDCAPC PPGHFSPGDNQACKPWTNCTLAGKH TLQPASNSSDAICEDRDPPATQPQE TQGPPARPITVQPTEAWPRTSQGPS TRPVEVPGGRA |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/mL (determined by absorbance at 280nm) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | TNFRSF4 TNF receptor superfamily member 4 [ Homo sapiens (human) ] |
Official Symbol : | TNFRSF4 |
Synonyms : | TNFRSF4; TNF receptor superfamily member 4; OX40; ACT35; CD134; IMD16; TXGP1L; tumor necrosis factor receptor superfamily member 4; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; lymphoid activation antigene ACT35; tax-transcriptionally activated glycoprotein 1 receptor |
Gene ID : | 7293 |
mRNA Refseq : | NM_003327 |
Protein Refseq : | NP_003318 |
MIM : | 600315 |
UniProt ID : | P43489 |
Products Types
◆ Recombinant Protein | ||
TNFRSF4-682M | Recombinant Mouse TNFRSF4 Protein | +Inquiry |
TNFRSF4-684R | Recombinant Rabbit TNFRSF4 Protein, Fc-tagged | +Inquiry |
TNFRSF4-2221H | Recombinant Human TNFRSF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF4-393H | Active Recombinant Human TNFRSF4 Protein (Met1-Ala216), His-tagged, Biotinylated | +Inquiry |
TNFRSF4-687M | Recombinant Mouse TNFRSF4 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF4-2422HCL | Recombinant Human TNFRSF4 cell lysate | +Inquiry |
TNFRSF4-1762MCL | Recombinant Mouse TNFRSF4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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