| Description : |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
64.6 kDa |
| Protein Length : |
595 |
| AA Sequence : |
MRVLLAALGLLFLGALRAFPQDRPF EDTCHGNPSHYYDKAVRRCCYRCPM GLFPTQQCPQRPTDCRKQCEPDYYL DEADRCTACVTCSRDDLVEKTPCAW NSSRVCECRPGMFCSTSAVNSCARC FFHSVCPAGMIVKFPGTAQKNTVCE PASPGVSPACASPENCKEPSSGTIP QAKPTPVSPATSSASTMPVRGGTRL AQEAASKLTRAPDSPSSVGRPSSDP GLSPTQPCPEGSGDCRKQCEPDYYL DEAGRCTACVSCSRDDLVEKTPCAW NSSRTCECRPGMICATSATNSCARC VPYPICAAETVTKPQDMAEKDTTFE APPLGTQPDCNPTPENGEAPASTSP TQSLLVDSQASKTLPIPTSAPVALS STGKPVLDAGPVLFWVILVLVVVVG SSAFLLCHRRACRKRIRQKLHLCYP VQTSQPKLELVDSRPRRSSTQLRSG ASVTEPVAEERGLMSQPLMETCHSV GAAYLESLPLQDASPAGGPSSPRDL PEPRVSTEHTNNKIEKIYIMKADTV IVGTVKAELPEGRGLAGPAEPELEE ELEADHTPHYPEQETEPPLGSCSDV MLSVEEEGKEDPLPTAASGK |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
