Recombinant Human TNFSF13B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TNFSF13B-4019H
• Product Overview: TNFSF13B MS Standard C13 and N15-labeled recombinant protein (NP_006564) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 31.2 kDa
• AA Sequence: MDDSTEREQSRLTSCLKKREEMKLK ECVSILPRKESPSVRSSKDGKLLAA TLLLALLSCCLTVVSFYQVAALQGD LASLRAELQGHHAEKLPAGAGAPKA GLEEAPAVTAGLKIFEPPAPGEGNS SQNSRNKRAVQGPEETVTQDCLQLI ADSETPTIQKGSYTFVPWLLSFKRG SALEEKENKILVKETGYFFIYGQVL YTDKTYAMGHLIQRKKVHVFGDELS LVTLFRCIQNMPETLPNNSCYSAGI AKLEEGDELQLAIPRENAQISLDGD VTFFGALKLLTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TNFSF13B TNF superfamily member 13b [ Homo sapiens (human) ]
• Official Symbol: TNFSF13B
• Synonyms: TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b; TNFSF20; tumor necrosis factor ligand superfamily member 13B; BAFF; BLYS; CD257; TALL 1; TALL1; THANK; delta BAFF; Delta4 BAFF; B-lymphocyte stimulator; B-cell-activating factor; ApoL related ligand TALL-1; TNF homolog that activates apoptosis; dendritic cell-derived TNF-like molecule; tumor necrosis factor-like protein ZTNF4; TNF and ApoL-related leukocyte expressed ligand 1; tumor necrosis factor (ligand) superfamily, member 20; DTL; ZTNF4; TALL-1
• Gene ID: 10673
• mRNA Refseq: NM_006573
• Protein Refseq: NP_006564
• MIM: 603969
• UniProt ID: Q9Y275