Recombinant Human TRIM22 Protein, GST-His-tagged TRIM22-563H

Recombinant Human TRIM22 Protein, GST-His-tagged


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Recombinant Human TRIM22 Protein, GST-His-tagged

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Cat.No. : TRIM22-563H
Product Overview : Recombinant Human TRIM22, transcript variant 1, fused with N-terminal GST and C-terminal His was expressed in E. coli.
Description : The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants.
Source : E. coli
Tag : GST-His
Form : 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass : 84.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TRIM22 tripartite motif containing 22 [ Homo sapiens ]
Official Symbol : TRIM22
Synonyms : TRIM22; tripartite motif containing 22; E3 ubiquitin-protein ligase TRIM22; GPSTAF50; RNF94; STAF50; staf-50; RING finger protein 94; tripartite binding motif 22; tripartite motif-containing 22; tripartite motif protein TRIM22; 50 kDa-stimulated trans-acting factor; tripartite motif-containing protein 22; stimulated trans-acting factor (50 kDa);
Gene ID : 10346
mRNA Refseq : NM_001199573
Protein Refseq : NP_001186502
MIM : 606559
UniProt ID : Q8IYM9

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