Recombinant Human TRPC5 Protein (A2-L973 end), 8×His-MBP, Flag tagged

• Cat.No.: TRPC5-1269H
• Product Overview: Recombinant Human 8His-MBP-TEV-(GG)-TRPC5(A2-L973 end)-Flag Protein was expressed in Mammalian cell.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Flag&His&MBP
• Protein Length: A2-L973 end
• Description: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1.
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 20 mM HEPES (pH 7.5), 150 mM NaCl, 0.005% GDN, 0.0005% CHS
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: TRPC5 transient receptor potential cation channel, subfamily C, member 5 [ Homo sapiens (human) ]
• Official Symbol: TRPC5
• Synonyms: TRPC5; transient receptor potential cation channel, subfamily C, member 5; short transient receptor potential channel 5; TRP-5; hTRP5; transient receptor protein 5; transient receptor potential channel 5; TRP5
• Gene ID: 7224
• mRNA Refseq: NM_012471
• Protein Refseq: NP_036603
• MIM: 300334
• UniProt ID: Q9UL62