Recombinant Human TSC22 Domain Family, Member 3, His-tagged TSC22D3-7192H

Recombinant Human TSC22 Domain Family, Member 3, His-tagged


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Cat.No. : TSC22D3-7192H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human TSC22D3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 17.2 kDa.
Description : TSC22 domain family protein 3, also known as TSC22D3, protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, TSC22D3 plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, TSC22D3 inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT.
Molecular Mass : 17.2 kDa (157aa) confirmed by MALDI-TOF
Protein length : 1-134aa
Purity : >85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : TSC22D3 TSC22 domain family, member 3 [ Homo sapiens ]
Official Symbol : TSC22D3
Synonyms : TSC22D3; TSC22 domain family, member 3; delta sleep inducing peptide, immunoreactor , DSIPI; TSC22 domain family protein 3; DIP; GILZ; glucocorticoid induced leucine zipper; hDIP; TSC 22R; TSC-22-like protein; TSC-22 related protein; TSC-22-related protein; DSIP-immunoreactive peptide; DSIP-immunoreactive leucine zipper protein; delta sleep-inducing peptide immunoreactor; delta sleep inducing peptide, immunoreactor; glucocorticoid-induced leucine zipper protein; DSIPI; TSC-22R; DKFZp313A1123;
Gene ID : 1831
mRNA Refseq : NM_001015881
Protein Refseq : NP_001015881
MIM : 300506
UniProt ID : Q99576
Chromosome Location : Xq22.3
Function : sequence-specific DNA binding transcription factor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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