Recombinant Human TSHR protein, His&Fc&Avi-tagged

• Cat.No.: TSHR-33H
• Product Overview: Purified recombinant protein of Human thyroid stimulating hormone receptor (TSHR), transcript variant 1, Met22-Gly413, with C-terminal Human FC-AVI plus and His tag, expressed in CHO cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&Fc&His
• Protein Length: Met22-Gly413
• Description: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
• Tag: His&Fc&Avi
• Molecular Mass: 74.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80°C after receiving vials.
• Concentration: >0.05 μg/μL as determined by microplate BCA method
• Storage Buffer: PBS, pH 7.4, 10% glycerol

Gene Information

• Gene Name: TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
• Official Symbol: TSHR
• Synonyms: CHNG1; hTSHR-I; LGR3; TSHR
• Gene ID: 7253
• mRNA Refseq: NM_000369
• Protein Refseq: NP_000360
• MIM: 603372
• UniProt ID: P16473