Recombinant Human TTR Protein
Cat.No. : | TTR-072H |
Product Overview : | Recombinant human TTR protein without tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. |
Source : | HEK293 |
Species : | Human |
Form : | Lyophilized |
Molecular Mass : | 14.6 kDa |
Protein Length : | 147 |
AA Sequence : | MASHRLLLLCLAGLVFVSEAGPTGT GESKCPLMVKVLDAVRGSPAINVAV HVFRKAADDTWEPFASGKTSESGEL HGLTTEEEFVEGIYKVEIDTKSYWK ALGISPFHEHAEVVFTANDSGPRRY TIAALLSPYSYSTTAVVTNPKE |
Purity : | > 98% |
Applications : | WB; ELISA; FACS; FC |
Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : | At -20 centigrade. |
Concentration : | 1 mg/mL |
Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
Gene Name : | TTR transthyretin [ Homo sapiens (human) ] |
Official Symbol : | TTR |
Synonyms : | TTR; transthyretin; PALB, prealbumin, amyloidosis type I; HsT2651; ATTR; carpal tunnel syndrome 1; thyroxine-binding prealbumin; prealbumin, amyloidosis type I; CTS; CTS1; PALB; TBPA; |
Gene ID : | 7276 |
mRNA Refseq : | NM_000371 |
Protein Refseq : | NP_000362 |
MIM : | 176300 |
UniProt ID : | P02766 |
Products Types
◆ Recombinant Protein | ||
TTR-2922H | Recombinant Human TTR Protein, MYC/DDK-tagged | +Inquiry |
Ttr-6725M | Recombinant Mouse Ttr Protein, Myc/DDK-tagged | +Inquiry |
TTR-2774H | Recombinant Human TTR Protein, His-tagged | +Inquiry |
TTR-04H | Recombinant Human TTR (L55P) Protein (Full Length) | +Inquiry |
TTR-6008R | Recombinant Rat TTR Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
TTR-31108TH | Native Human TTR | +Inquiry |
TTR-131H | Native Human Prealbumin protein | +Inquiry |
TTR-141S | Native Sheep prealbumin | +Inquiry |
◆ Lysates | ||
TTR-2149HCL | Recombinant Human TTR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket