Recombinant Human TULP3 protein, MYC/DDK-tagged

• Cat.No.: TULP3-213H
• Product Overview: Recombinant Human TULP3 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Protein Length: 1-442 aa
• Description: This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TULP3 tubby like protein 3 [ Homo sapiens ]
• Official Symbol: TULP3
• Synonyms: TULP3; tub; tubby-related protein 3; TUBL3; tubby-like protein 3; MGC45295
• Gene ID: 7289
• mRNA Refseq: NM_003324
• Protein Refseq: NP_003315
• MIM: 604730
• UniProt ID: O75386
• Chromosome Location: 12p13
• Function: phosphatidylinositol-4,5-bisphosphate binding