Recombinant Human TULP3 protein, MYC/DDK-tagged TULP3-213H

Recombinant Human TULP3 protein, MYC/DDK-tagged


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Recombinant Human TULP3 protein, MYC/DDK-tagged

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Cat.No. : TULP3-213H
Product Overview : Recombinant Human TULP3 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 49.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TULP3 tubby like protein 3 [ Homo sapiens ]
Official Symbol : TULP3
Synonyms : TULP3; tub; tubby-related protein 3; TUBL3; tubby-like protein 3; MGC45295;
Gene ID : 7289
mRNA Refseq : NM_003324
Protein Refseq : NP_003315
MIM : 604730
UniProt ID : O75386
Chromosome Location : 12p13
Function : phosphatidylinositol-4,5-bisphosphate binding;

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