Recombinant Human TXNDC Protein, MYC/DDK-tagged

• Cat.No.: TXNDC5-1108H
• Product Overview: Recombinant protein of human thioredoxin domain containing 5 (endoplasmic reticulum) (TXNDC5), transcript variant 1 was expressed in HEK 293 cells with C-terminal MYC/DDK tag.

Specification

• Description: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 44.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TXNDC5 thioredoxin domain containing 5 [ Homo sapiens (human) ]
• Official Symbol: TXNDC5
• Synonyms: TXNDC5; thioredoxin domain containing 5 (endoplasmic reticulum); thioredoxin domain containing 5; thioredoxin domain-containing protein 5; EndoPDI; ERp46; FLJ21353; FLJ90810; Hcc 2; MGC3178; PDIA15; protein disulfide isomerase family A; member 15; ER protein 46; thioredoxin related protein; thioredoxin-like protein p46; endoplasmic reticulum protein ERp46; endothelial protein disulphide isomerase; endoplasmic reticulum resident protein 46; protein disulfide isomerase family A, member 15; ERP46; HCC-2; STRF8; UNQ364; ENDOPDI; FLJ21789
• Gene ID: 81567
• mRNA Refseq: NM_030810.4
• Protein Refseq: NP_110437
• MIM: 616412
• UniProt ID: Q8NBS9