Recombinant Human TYMP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TYMP-5920H
• Product Overview: TYMP MS Standard C13 and N15-labeled recombinant protein (NP_001944) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50 kDa
• AA Sequence: MAALMTPGTGAPPAPGDFSGEGSQG LPDPSPEPKQLPELIRMKRDGGRLS EADIRGFVAAVVNGSAQGAQIGAML MAIRLRGMDLEETSVLTQALAQSGQ QLEWPEAWRQQLVDKHSTGGVGDKV SLVLAPALAACGCKVPMISGRGLGH TGGTLDKLESIPGFNVIQSPEQMQV LLDQAGCCIVGQSEQLVPAEGILYA ARDVTATVDSLPLITASILSKKLVE GLSALVVDVKFGGAAVFPNQEQARE LAKTLVGVGASLGLRVAAALTAMDK PLGRCVGHALEVEEALLCMDGAGPP DLRDLVTTLGGALLWLSGHAGTQAQ GAARVAAALDDGSALGRFERMLAAQ GVDPGLARALCSGSPAERRQLLPRA REQEELLAPADGTVELVRALPLALV LHELGAGRSRAGEPLRLGVGAELLV DVGQRLRRGTPWLRVHRDGPALSGP QSRALQEALVLSDRAPFAAPSPFAE LVLPPQQTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TYMP thymidine phosphorylase [ Homo sapiens (human) ]
• Official Symbol: TYMP
• Synonyms: TYMP; thymidine phosphorylase; ECGF1, endothelial cell growth factor 1 (platelet derived), MNGIE; gliostatin; tdRPase; TP; ECGF; ECGF1; MNGIE; MEDPS1; MTDPS1; PDECGF; hPD-ECGF
• Gene ID: 1890
• mRNA Refseq: NM_001953
• Protein Refseq: NP_001944
• MIM: 131222
• UniProt ID: P19971