Recombinant Human UCHL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UCHL1-6106H
• Product Overview: UCHL1 MS Standard C13 and N15-labeled recombinant protein (NP_004172) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 24.8 kDa
• AA Sequence: MQLKPMEINPEMLNKVLSRLGVAGQ WRFVDVLGLEEESLGSVPAPACALL LLFPLTAQHENFRKKQIEELKGQEV SPKVYFMKQTIGNSCGTIGLIHAVA NNQDKLGFEDGSVLKQFLSETEKMS PEDRAKCFEKNEAIQAAHDAVAQEG QCRVDDKVNFHFILFNNVDGHLYEL DGRMPFPVNHGASSEDTLLKDAAKV CREFTEREQGEVRFSAVALCKAATR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UCHL1 ubiquitin C-terminal hydrolase L1 [ Homo sapiens (human) ]
• Official Symbol: UCHL1
• Synonyms: UCHL1; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); PARK5; ubiquitin carboxyl-terminal hydrolase isozyme L1; PGP9.5; Uch L1; ubiquitin thioesterase L1; neuron cytoplasmic protein 9.5; ubiquitin C-terminal hydrolase; PGP95; Uch-L1; PGP 9.5
• Gene ID: 7345
• mRNA Refseq: NM_004181
• Protein Refseq: NP_004172
• MIM: 191342
• UniProt ID: P09936