Recombinant Human UHRF2 protein, MYC/DDK-tagged UHRF2-10H

Recombinant Human UHRF2 protein, MYC/DDK-tagged


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Recombinant Human UHRF2 protein, MYC/DDK-tagged

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Cat.No. : UHRF2-10H
Product Overview : Recombinant Human UHRF2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 89.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase [ Homo sapiens ]
Official Symbol : UHRF2
Synonyms : UHRF2; ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase; ubiquitin like with PHD and ring finger domains 2; E3 ubiquitin-protein ligase UHRF2; MGC33463; NIRF; Np95 like ring finger protein; RNF107; URF2; nuclear protein 97; RING finger protein 107; Np95-like ring finger protein; nuclear zinc finger protein NP97; np95/ICBP90-like RING finger protein; ubiquitin-like, containing PHD and RING finger domains, 2; ubiquitin-like PHD and RING finger domain-containing protein 2; ubiquitin-like-containing PHD and RING finger domains protein 2; RP11-472F14.2; DKFZp434B0920; DKFZp686G0837;
Gene ID : 115426
mRNA Refseq : NM_152896
Protein Refseq : NP_690856
UniProt ID : Q96PU4
Chromosome Location : 9p24.1
Function : DNA binding; histone binding; ligase activity; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;

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