| Description : |
This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
59.7 kDa |
| AA Sequence : |
MEAPTVETPPDPSPPSAPAPALVPL RAPDVARLREEQEKVVTNCQERIQH WKKVDNDYNALRERLSTLPDKLSYN IMVPFGPFAFMPGKLVHTNEVTVLL GDNWFAKCSAKQAVGLVEHRKEHVR KTIDDLKKVMKNFESRVEFTEDLQK MSDAAGDIVDIREEIKCDFEFKAKH RIAHKPHSKPKTSDIFEADIANDVK SKDLLADKELWARLEELERQEELLG ELDSKPDTVIANGEDTTSSEEEKED RNTNVNAMHQVTDSHTPCHKDVASS EPFSGQVNSQLNCSVNGSSSYHSDD DDDDDDDDDDDNIDDDDGDNDHEAL GVGDNSIPTIYFSHTVEPKRVRINT GKNTTLKFSEKKEEAKRKRKNSTGS GHSAQELPTIRTPADIYRAFVDVVN GEYVPRKSILKSRSRENSVCSDTSE SSAAEFDDRRGVLRSISCEEATCSD TSESILEEEPQENQKKLLPLSVTPE AFSGTVIEKEFVSPSLTPPPAIAHP ALPTIPERKEVLLEASEETGKRVSK FKAARLQQKDTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
