Recombinant Human USP14 Protein (Q96-Q494), Tag Free
Cat.No. : | USP14-0900H |
Product Overview : | Recombinant Human USP14(Q96-Q494 end) Protein was expressed in E. coli. |
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Description : | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. |
Source : | E. coli |
Species : | Human |
Tag : | Non |
Form : | Liquid |
Protein length : | Q96-Q494 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) [ Homo sapiens (human) ] |
Official Symbol : | USP14 |
Synonyms : | USP14; ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase); ubiquitin specific protease 14 (tRNA guanine transglycosylase); ubiquitin carboxyl-terminal hydrolase 14; TGT; ubiquitin thioesterase 14; deubiquitinating enzyme 14; ubiquitin thiolesterase 14; ubiquitin-specific processing protease 14; ubiquitin-specific-processing protease 14; tRNA-guanine transglycosylase, 60-kD subunit; ubiquitin specific protease 14 (tRNA-guanine transglycosylase); |
Gene ID : | 9097 |
mRNA Refseq : | NM_001037334 |
Protein Refseq : | NP_001032411 |
MIM : | 607274 |
UniProt ID : | P54578 |
Products Types
◆ Recombinant Protein | ||
USP14-4934R | Recombinant Rhesus Macaque USP14 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP14-0899H | Recombinant Human USP14 Protein (Q96-Q494), His tagged | +Inquiry |
Usp14-6865M | Recombinant Mouse Usp14 Protein, Myc/DDK-tagged | +Inquiry |
USP14-01H | Active Recombinant Human USP14 Protein | +Inquiry |
USP14-3641H | Recombinant Human USP14 protein, His-tagged | +Inquiry |
◆ Lysates | ||
USP14-471HCL | Recombinant Human USP14 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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