Recombinant Human USP16 Protein (G2-L823), Tag Free

Cat.No. : USP16-1219H
Product Overview : Recombinant Human GG-USP16(G2-L823 end) Protein was expressed in Insect cell.
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Description : Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
Source : Insect cell
Species : Human
Tag : Non
Form : Liquid
Protein length : G2-L823
Endotoxin : < 0.01 EU per μg of the protein
Purity : 90%
Stability : Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Shipping : It is shipped out with blue ice.
Gene Name : USP16 ubiquitin specific peptidase 16 [ Homo sapiens (human) ]
Official Symbol : USP16
Synonyms : USP16; ubiquitin specific peptidase 16; UBPM; UBP-M; ubiquitin carboxyl-terminal hydrolase 16; deubiquitinating enzyme 16; ubiquitin specific protease 16; ubiquitin thioesterase 16; ubiquitin thiolesterase 16; ubiquitin-processing protease UBP-M; ubiquitin-specific processing protease 16; EC 3.4.19.12
Gene ID : 10600
mRNA Refseq : NM_006447
Protein Refseq : NP_006438
MIM : 604735
UniProt ID : Q9Y5T5

Not For Human Consumption!

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