Recombinant Human USP16 Protein (G2-L823), Tag Free
Cat.No. : | USP16-1219H |
Product Overview : | Recombinant Human GG-USP16(G2-L823 end) Protein was expressed in Insect cell. |
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Description : | Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. |
Source : | Insect cell |
Species : | Human |
Tag : | Non |
Form : | Liquid |
Protein length : | G2-L823 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | USP16 ubiquitin specific peptidase 16 [ Homo sapiens (human) ] |
Official Symbol : | USP16 |
Synonyms : | USP16; ubiquitin specific peptidase 16; UBPM; UBP-M; ubiquitin carboxyl-terminal hydrolase 16; deubiquitinating enzyme 16; ubiquitin specific protease 16; ubiquitin thioesterase 16; ubiquitin thiolesterase 16; ubiquitin-processing protease UBP-M; ubiquitin-specific processing protease 16; EC 3.4.19.12 |
Gene ID : | 10600 |
mRNA Refseq : | NM_006447 |
Protein Refseq : | NP_006438 |
MIM : | 604735 |
UniProt ID : | Q9Y5T5 |
Products Types
◆ Recombinant Protein | ||
USP16-362H | Recombinant Human USP16 Protein, His-tagged | +Inquiry |
USP16-4936R | Recombinant Rhesus Macaque USP16 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP16-6127R | Recombinant Rat USP16 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP16-1218H | Recombinant Human USP16 Protein (G2-L823), His tagged | +Inquiry |
Usp16-6867M | Recombinant Mouse Usp16 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
USP16-470HCL | Recombinant Human USP16 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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