Recombinant Human USP2, His-tagged
Cat.No. : | USP2-153H |
Product Overview : | Recombinant Human USP2core protein, fused with His6 tag, was expressed in E. coli. |
- Specification
- Gene Information
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Description : | USP2 core represents the common catalytic core domain of the two isoforms of USP2, USP2a and USP2b. In vitro studies revealed that the USP2 core was able to deubiquitylate high molecular weight proteins from testis extracts and cleave Ub-PLA2 with good efficiency. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid, 50mM Hepes, pH8, 150mM NaCl, 5mM DTT, 10% glycerol |
Molecular Mass : | 40kDa |
Storage : | Store at -80°C, avoiding repeated freeze-thaw cycles. |
Gene Name : | USP2 ubiquitin specific peptidase 2 [ Homo sapiens ] |
Official Symbol : | USP2 |
Synonyms : | USP2; ubiquitin specific peptidase 2; ubiquitin specific protease 2; ubiquitin carboxyl-terminal hydrolase 2; UBP41; ubiquitin thioesterase 2; deubiquitinating enzyme 2; ubiquitin specific protease 9; ubiquitin specific protease 12; 41 kDa ubiquitin-specific protease; ubiquitin-specific-processing protease 2; USP9; |
Gene ID : | 9099 |
mRNA Refseq : | NM_001243759 |
Protein Refseq : | NP_001230688 |
MIM : | 604725 |
UniProt ID : | O75604 |
Chromosome Location : | 11q23.3 |
Pathway : | TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem; |
Function : | cyclin binding; cysteine-type endopeptidase activity; identical protein binding; metal ion binding; peptidase activity; protein binding; ubiquitin protein ligase binding; ubiquitin thiolesterase activity; ubiquitin thiolesterase activity; |
Products Types
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USP2-9951M | Recombinant Mouse USP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP2-092H | Recombinant Human USP2 Protein, His-tagged | +Inquiry |
USP2-0550H | Recombinant Human USP2 Protein (N259-M605), His tagged | +Inquiry |
USP2-011H | Recombinant Human USP2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
USP2-468HCL | Recombinant Human USP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionIt's possible. Elevated levels of USP2 have been associated with certain cancers and metabolic disorders, suggesting its potential as a biomarker for disease diagnosis and prognosis.
There's research interest in exploring USP2 inhibitors to potentially improve insulin sensitivity and manage diabetes, but clinical trials in this area are still in early stages.
Yes, several studies are investigating USP2 inhibitors as potential therapeutic agents in cancer treatment to target specific pathways involved in tumor growth.
USP2 has been shown to regulate insulin signaling by deubiquitinating proteins involved in insulin receptor signaling pathways. Dysregulation of USP2 may contribute to insulin resistance in diabetes.
Yes, due to its role in regulating protein stability, USP2 is being considered as a potential therapeutic target for drug development, especially in cancer and other diseases involving dysregulated protein turnover.
Customer Reviews (3)
Write a reviewIts versatility and reliability make it a great asset in the pursuit of scientific discoveries.
With the USP2 protein, researchers can confidently delve into the complexity of protein structures and gain deeper insights into their functions.
The USP2 protein's exceptional quality and purity guarantee its suitability for a wide range of experimental applications.
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