Recombinant Human USP39 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: USP39-413H
• Product Overview: USP39 MS Standard C13 and N15-labeled recombinant protein (NP_006581) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 65.4 kDa
• AA Sequence: MSGRSKRESRGSTRGKRESESRGSS GRVKRERDREREPEAASSRGSPVRV KREFEPASAREAPASVVPFVRVKRE REVDEDSEPEREVRAKNGRVDSEDR RSRHCPYLDTINRSVLDFDFEKLCS ISLSHINAYACLVCGKYFQGRGLKS HAYIHSVQFSHHVFLNLHTLKFYCL PDNYEIIDSSLEDITYVLKPTFTKQ QIANLDKQAKLSRAYDGTTYLPGIV GLNNIKANDYANAVLQALSNVPPLR NYFLEEDNYKNIKRPPGDIMFLLVQ RFGELMRKLWNPRNFKAHVSPHEML QAVVLCSKKTFQITKQGDGVDFLSW FLNALHSALGGTKKKKKTIVTDVFQ GSMRIFTKKLPHPDLPAEEKEQLLH NDEYQETMVESTFMYLTLDLPTAPL YKDEKEQLIIPQVPLFNILAKFNGI TEKEYKTYKENFLKRFQLTKLPPYL IFCIKRFTKNNFFVEKNPTIVNFPI TNVDLREYLSEEVQAVHKNTTYDLI ANIVHDGKPSEGSYRIHVLHHGTGK WYELQDLQVTDILPQMITLSEAYIQ IWKRRDNDETNQQGATRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: USP39 ubiquitin specific peptidase 39 [ Homo sapiens (human) ]
• Official Symbol: USP39
• Synonyms: USP39; ubiquitin specific peptidase 39; ubiquitin specific protease 39; U4/U6.U5 tri-snRNP-associated protein 2; CGI 21; SAD1; small nuclear ribonucleoprotein 65kDa (U4/U6.U5); snRNP assembly defective 1 homolog (S.cerevisiae); SNRNP65; SAD1 homolog; SnRNP assembly defective 1 homolog; inactive ubiquitin-specific peptidase 39; U4/U6.U5 tri-snRNP-associated 65 kDa protein; 65K; CGI-21; HSPC332; FLJ33136; MGC75069
• Gene ID: 10713
• mRNA Refseq: NM_006590
• Protein Refseq: NP_006581
• MIM: 611594
• UniProt ID: Q53GS9