Recombinant Human USP5 Protein (A2-S858), His tagged
Cat.No. : | USP5-0299H |
Product Overview : | Recombinant Human 6His-TEV-GG-USP5(A2-S858 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Protein Length : | A2-S858 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | USP5 ubiquitin specific peptidase 5 (isopeptidase T) [ Homo sapiens (human) ] |
Official Symbol : | USP5 |
Synonyms : | USP5; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5 (isopeptidase T); ubiquitin carboxyl-terminal hydrolase 5; IsoT; isopeptidase T; ubiquitin isopeptidase T; ubiquitin thioesterase 5; deubiquitinating enzyme 5; ubiquitin thiolesterase 5; ubiquitin-specific-processing protease 5; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); ISOT; |
Gene ID : | 8078 |
mRNA Refseq : | NM_001098536 |
Protein Refseq : | NP_001092006 |
MIM : | 601447 |
UniProt ID : | P45974 |
Products Types
◆ Recombinant Protein | ||
Usp5-6881M | Recombinant Mouse Usp5 Protein, Myc/DDK-tagged | +Inquiry |
USP5-681H | Recombinant Human USP5 Protein, MYC/DDK-tagged | +Inquiry |
USP5-9973M | Recombinant Mouse USP5 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP5-4943R | Recombinant Rhesus Macaque USP5 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP5-0300H | Recombinant Human USP5 Protein (A2-S858), Tag Free | +Inquiry |
◆ Lysates | ||
USP5-561HCL | Recombinant Human USP5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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