Recombinant Human USP5 Protein, MYC/DDK-tagged

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Recombinant Human USP5 Protein, MYC/DDK-tagged

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Cat.No. : USP5-681H
Product Overview : Recombinant human USP5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 93.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ubiquitin specific peptidase 5[ Homo sapiens ]
Official Symbol : USP5
Synonyms : ISOT
Gene ID : 8078
Protein Refseq : NP_003472
MIM : 601447
UniProt ID : P45974

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