Recombinant Human USP9Y Protein (R1553-S1972), Tag Free
| Cat.No. : | USP9Y-0641H |
| Product Overview : | Recombinant Human GG-USP9Y(R1553-S1972) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade. Deubiquitination of SMAD4 by USP9X re-empowers its competence to mediate TGF-beta signaling. |
| Source : | E. coli |
| Species : | Human |
| Tag : | No tag |
| Form : | Liquid |
| Protein Length : | R1553-S1972 |
| Endotoxin : | < 0.01 EU per μg of the protein |
| Purity : | 90% |
| Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
| Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
| Shipping : | It is shipped out with blue ice. |
| Gene Name : | USP9Y ubiquitin specific peptidase 9, Y-linked [ Homo sapiens (human) ] |
| Official Symbol : | USP9Y |
| Synonyms : | USP9Y; ubiquitin specific peptidase 9, Y-linked; ubiquitin specific peptidase 9, Y linked (fat facets like, Drosophila); probable ubiquitin carboxyl-terminal hydrolase FAF-Y; DFFRY; fat facets like homolog (Drosophila); ubiquitin thioesterase FAF-Y; deubiquitinating enzyme FAF-Y; ubiquitin thiolesterase FAF-Y; fat facets protein-related, Y-linked; ubiquitin-specific protease 9, Y chromosome; ubiquitin-specific processing protease FAF-Y; ubiquitin-specific-processing protease FAF-Y; ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila); SPGFY2; FLJ33043; |
| Gene ID : | 8287 |
| mRNA Refseq : | NM_004654 |
| Protein Refseq : | NP_004645 |
| MIM : | 400005 |
| UniProt ID : | O00507 |
Products Types
| ◆ Recombinant Protein | ||
| USP9Y-0640H | Recombinant Human USP9Y Protein (R1553-S1972), GST tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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