Recombinant Human UVSSA Protein, MYC/DDK-tagged

• Cat.No.: UVSSA-816H
• Product Overview: Recombinant human UVSSA protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 80.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: UV stimulated scaffold protein A[ Homo sapiens ]
• Official Symbol: UVSSA
• Synonyms: KIAA1530; UVSS3
• Gene ID: 57654
• mRNA Refseq: NM_020894.2
• Protein Refseq: NP_065945
• MIM: 614632
• UniProt ID: Q2YD98