Recombinant Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (avian), Thyrodoxin Tagged and His Tagged
Cat.No. : | ERBB3-5193H |
Product Overview : | Recombinant HumanTyrosine Kinase ERBB3 (extracellular domain) is a single, non- glycosylated,fusion polypeptide chain containing Thyrodoxin Tag and His tag. The proteinconsists of 190 amino acids (Met1- Cys190). ERBB3 is expressed in E. coli, MW 34kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ERBB3-5193H |
Description : | Receptortyrosine-protein kinase ERBB3 is an enzyme that in humans is encoded by theERBB3 gene. This gene encodes a member of the epidermal growth factorreceptor (EGFR) family of receptor tyrosine kinases. This membrane-boundprotein has a neuregulin binding domain but not an active kinase domain. |
Source : | Human |
Host : | E. coli |
Form : | Liquid. Each mg ofprotein contains 1 mg aluminum hydroxide + 10 mM arginine + 10 mM sodiumchloride + 20 mM sodium phosphate buffer + 5 mM potassium. phosphate. |
Purity : | > 95.0% asdetermined by RP-HPLC and SDS-PAGE analyses. |
Sequence : | MRANDALQVLGLLFSLARGS EVGNSQAVCP GTLNGLSVTG DAENQYQTLY KLYERCEVVM GNLEIVLTGH NADLSFLQWIREVTGYVLVA MNEFSTLPLP NLRVVRGTQV YDGKFAIFVM LNYNTNSSHA LRQLRLTQLT EILSGGVYIE KNDKLCHMDTIDWRDIVRDR DAEIVVKDNG RSCPPCHEVC |
Molecular Weight : | 34 kDa |
Biological Activity : | Determined by itsability to postpone tumor emerge time of spontaneous breast cancer in FVB/Ntransgenic mice and inhibit the development of tumor and growth of in situ transplantedbreast cancer in FVB/N transgenic mice. |
Endotoxin Level : | < 0.1 ng/µg ofERBB3 |
Storage : | Store at -20°C to-80°C with a carrier protein (0.1% HSA or BSA) as a stabilizer for long termstorage. Please note that the addition of any carrier protein into this productmay produce unwanted endotoxin. This depends upon the particular application employed.Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | ERBB3 |
Gene Name : | ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [ Homosapiens ] |
Synonyms : | ERBB3;v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); HER3;LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; MGC88033; c-erbB-3; p180-ErbB3;p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-likeprotein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; EC2.7.10.1; EC 2.7.10 |
Gene ID : | 2065 |
mRNA Refseq : | NM_001005915 |
Protein Refseq : | NP_001005915 |
MIM : | 190151 |
UniProt ID : | P21860 |
Chromosome Location : | 12q13 |
Pathway : | Calcium signalingpathway; Endocytosis; ErbB receptor signaling network; ErbB signalingpathway; ErbB2/ErbB3 signaling events; Heart Development; IL-6 SignalingPathway; a6b1 and a6b4 Integrin signaling |
Function : | ATP binding; growthfactor binding; nucleotide binding; protein binding; proteinheterodimerization activity; protein tyrosine kinase activator activity; NOTprotein tyrosine kinase activity; receptor activity; receptor signalingprotein tyrosine kinase activity; transmembrane receptor protein tyrosinekinase activity; transmembrane signaling receptor activity |
Products Types
◆ Recombinant Protein | ||
ERBB3-238H | Recombinant Human ERBB3 Protein, Strep-tagged | +Inquiry |
ERBB3-858H | Recombinant Human ERBB3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERBB3-237H | Recombinant Human ERBB3 Protein, Fc-tagged | +Inquiry |
ERBB3-235H | Recombinant Human ERBB3 Protein, His-tagged, Biotinylated | +Inquiry |
Erbb3-7437R | Recombinant Rat Erbb3 Protein(Met1-His641), His-tagged | +Inquiry |
◆ Lysates | ||
ERBB3-939HCL | Recombinant Human ERBB3 cell lysate | +Inquiry |
ERBB3-1415RCL | Recombinant Rat ERBB3 cell lysate | +Inquiry |
ERBB3-1721RCL | Recombinant Rhesus ERBB3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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