Creative BioMart to Present at BPS 2025 Annual Meeting | February 15-19, 2025

Recombinant Human v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) Protein, His-tagged

Cat.No. : SRC-001H
Product Overview : Recombinant Human SRC Protein (1-79aa) with C-His-tag was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Source : E. coli
Species : Human
Tag : C-His
Protein length : 1-79aa
Molecular Mass : 9 kDa
AA Sequence : MGSNKSKPKDASQRRRSLEPAENVH GAGGGAFPASQTPSKPASADGHRGP SAAFAPAAAEPKLFGGFNSSDTVTS PQRAHHHHHHHH
Endotoxin : < 1 EU/μg by LAL.
Purity : > 90 % by SDS-PAGE
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Concentration : 1 mg/mL by BCA
Storage Buffer : Sterile PBS, pH7.4
Gene Name : SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [Homo sapiens (human)]
Official Symbol : SRC
Synonyms : SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); SRC1, v src avian sarcoma (Schmidt Ruppin A 2) viral oncogene homolog; proto-oncogene tyrosine-protein kinase Src; ASV; c src; proto-oncogene c-Src; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; protooncogene SRC, Rous sarcoma; SRC1; c-SRC; p60-Src
Gene ID : 6714
mRNA Refseq : NM_005417
Protein Refseq : NP_005408
MIM : 190090
UniProt ID : P12931

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
01/01/2022

    Top-notch protein purification service, essential for our research.

    08/29/2019

      Reliable mass spectrometry analysis, pivotal for our proteomics work.

      03/02/2019

        Swift and reliable protein sequencing, indispensable for our research success.

        Q&As (7)

        Ask a question
        How do alterations in SRC expression or activity affect the development of drug resistance in tumors? 10/23/2022

        Changes in SRC expression or kinase activity can lead to drug resistance in cancer treatment.

        How does SRC (proto-oncogene tyrosine-protein kinase Src) regulate cell proliferation and survival? 07/08/2021

        SRC regulates cell proliferation and survival through its kinase activity, influencing various signaling pathways.

        How does SRC contribute to the regulation of bone remodeling and osteoclast activity? 06/26/2020

        SRC is involved in bone remodeling, regulating osteoclast activity and bone resorption.

        What role does SRC play in cancer development and progression, particularly in metastasis? 03/16/2020

        SRC plays a crucial role in cancer progression, particularly in enhancing metastatic potential of tumor cells.

        How does SRC influence cellular signaling pathways, such as the Ras/MAPK and PI3K/Akt pathways? 12/06/2019

        SRC influences key cellular signaling pathways like Ras/MAPK and PI3K/Akt, affecting cell growth and survival.

        What are the mechanisms by which SRC modulates cellular adhesion and migration? 03/27/2019

        SRC modulates cellular adhesion and migration, playing a role in tissue repair and cancer metastasis.

        What is the impact of SRC inhibition on targeted cancer therapies? 01/02/2018

        SRC inhibition is a target in cancer therapy, potentially reducing tumor growth and metastasis.

        Ask a Question for All SRC Products

        Required fields are marked with *

        My Review for All SRC Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2025 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends