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Recombinant Human VCP, GST-tagged

Cat.No. : VCP-3656H
Product Overview : Recombinant Human VCP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-300aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : VCP valosin containing protein [ Homo sapiens ]
Official Symbol : VCP
Synonyms : VCP; valosin containing protein; transitional endoplasmic reticulum ATPase; IBMPFD; p97; TER ATPase; yeast Cdc48p homolog; valosin-containing protein; 15S Mg(2+)-ATPase p97 subunit; TERA; ALS14; MGC8560; MGC131997; MGC148092;
Gene ID : 7415
mRNA Refseq : NM_007126
Protein Refseq : NP_009057
MIM : 601023
UniProt ID : P55072
Chromosome Location : 9p13
Pathway : DNA Repair, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; HRD1/SEL1 ERAD complex, organism-specific biosystem; HRD1/SEL1 ERAD complex, conserved biosystem; IL-9 Signaling Pathway, organism-specific biosystem; Legionello
Function : ATP binding; ATPase activity; hydrolase activity; identical protein binding; lipid binding; nucleotide binding; polyubiquitin binding; protein binding; protein domain specific binding; protein phosphatase binding; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can abnormalities in the VCP protein be detected through genetic testing? 10/10/2022

Yes, genetic testing can identify mutations in the VCP gene, aiding in the diagnosis of VCP-related disorders.

Can VCP protein levels be used as a diagnostic marker for specific diseases? 07/28/2021

Currently, VCP protein levels are not widely used as a diagnostic marker, but ongoing research may reveal its potential utility in the future.

Is the VCP protein a potential target for drug development? 01/08/2020

The potential therapeutic targeting of VCP is an area of active research, with efforts to develop drugs that modulate its activity for the treatment of specific diseases.

Can changes in the VCP protein be indicative of other health conditions besides neurodegenerative diseases and cancer? 06/30/2017

Yes, alterations in VCP function may contribute to various health conditions, including autoimmune diseases and metabolic disorders.

How does the VCP protein relate to cellular protein quality control? 03/28/2016

VCP plays a crucial role in eliminating misfolded or damaged proteins, contributing to cellular protein quality control mechanisms.

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08/19/2022

    This can involve organizing conferences, workshops, and webinars to discuss the latest advancements, share research findings, and broaden the understanding of VCP function.

    01/30/2022

      Researchers have successfully utilized VCP protein in electron microscopy studies, unraveling crucial insights into protein interactions and conformational changes.

      04/23/2019

        The exceptional performance of VCP protein in both ELISA and protein electron microscopy structure analysis positions it as a valuable tool in a broad range of research applications.

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