Recombinant Human Very Low Density Iipoprotein Receptor, His-tagged

• Cat.No.: VLDLR-4765H
• Product Overview: The recombinant human VLDLR comprises 781 amino acids with a predicted molecular mass of 86kDa. It migrates with the apparent molecular weight of 150 & 180kDa due to different glycosylation in SDS-PAGE under reducing conditions.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Description: The very-low-density-lipoprotein receptor (VLDL-R) is a lipoprotein receptor that shows considerable similarity to the low-density-lipoprotein receptor. VLDL R is a 130 kDa type I transmembrane protein in the LDL receptor family that plays a significant role in lipid metabolism and in nervous system development and function .This receptor has been suggested to be important for the metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, such as very-low-density-lipoprotein (VLDL), beta-migrating VLDL and intermediate-density lipoprotein.
• Form: Bulk protein in a 0.22 μm filtered solution of PBS, pH7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization.
• Purity: >95% as determined by SDS-PAGE. All lots are greater than 95% pure.
• Endotoxin: Less than 1.0 EU per 1 μg of the rhLIF by the LAL method.
• Storage: Store at -80°C upon received. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: VLDLR very low density lipoprotein receptor [ Homo sapiens ]
• Official Symbol: VLDLR
• Synonyms: VLDLR; very low density lipoprotein receptor; CHRMQ1; VLDLRCH; FLJ35024; VLDL-R; VLDL receptor; Very low-density lipoprotein receptor; OTTHUMP00000020983; OTTHUMP00000020982
• Gene ID: 7436
• mRNA Refseq: NM_001018056
• Protein Refseq: NP_001018066
• MIM: 192977
• UniProt ID: P98155
• Chromosome Location: 9p24
• Function: very-low-density lipoprotein receptor activity; low-density lipoprotein receptor activity; apolipoprotein binding; calcium ion binding; receptor activity