| Description : |
This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
100.6 kDa |
| AA Sequence : |
MHDAFEPVPILEKLPLQIDCLAAWE EWLLVGTKQGHLLLYRIRKDVGCNR FEVTLEKSNKNFSKKIQQIHVVSQF KILVSLLENNIYVHDLLTFQQITTV SKAKGASLFTCDLQHTETGEEVLRM CVAVKKKLQLYFWKDREFHELQGDF SVPDVPKSMAWCENSICVGFKRDYY LIRVDGKGSIKELFPTGKQLEPLVA PLADGKVAVGQDDLTVVLNEEGICT QKCALNWTDIPVAMEHQPPYIIAVL PRYVEIRTFEPRLLVQSIELQRPRF ITSGGSNIIYVASNHFVWRLIPVPM ATQIQQLLQDKQFELALQLAEMKDD SDSEKQQQIHHIKNLYAFNLFCQKR FDESMQVFAKLGTDPTHVMGLYPDL LPTDYRKQLQYPNPLPVLSGAELEK AHLALIDYLTQKRSQLVKKLNDSDH QSSTSPLMEGTPTIKSKKKLLQIID TTLLKCYLHTNVALVAPLLRLENNH CHIEESEHVLKKAHKYSELIILYEK KGLHEKALQVLVDQSKKANSPLKGH ERTVQYLQHLGTENLHLIFSYSVWV LRDFPEDGLKIFTEDLPEVESLPRD RVLGFLIENFKGLAIPYLEHIIHVW EETGSRFHNCLIQLYCEKVQGLMKE YLLSFPAGKTPVPAGEEEGELGEYR QKLLMFLEISSYYDPGRLICDFPFD GLLEERALLLGRMGKHEQALFIYVH ILKDTRMAEEYCHKHYDRNKDGNKD VYLSLLRMYLSPPSIHCLGPIKLEL LEPKANLQAALQVLELHHSKLDTTK ALNLLPANTQINDIRIFLEKVLEEN AQKKRFNQVLKNLLHAEFLRVQEER ILHQQVKCIITEEKVCMVCKKKIGN SAFARYPNGVVVHYFCSKEVNPADT TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
