"VSIR" Related Products

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Recombinant Human VSIR Protein, Avi/His-tagged

Cat.No. : VSIR-21H
Product Overview : Recombinant Human VSIR(Phe 33 - Ala 194) fused with Avi/His tag at the C-terminus was produced in HEK293.
Description : Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Source : HEK293
Species : Human
Tag : Avi/His
Predicted N Terminal : Phe 33
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Molecular Mass : The protein has a calculated MW of 20.8 kDa. As a result of glycosylation, the protein migrates as 35-45 kDa under reducing (R) condition, and 35-45 kDa under non-reducing (NR) condition (SDS-PAGE).
Protein length : Phe 33 - Ala 194
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
4-8 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Figure :

Gene Name : VSIR V-set immunoregulatory receptor [ Homo sapiens ]
Official Symbol : VSIR
Synonyms : B7H5; GI24; B7-H5; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha; V-domain Ig suppressor of T cell activation; V-set domain-containing immunoregulatory receptor; platelet receptor GI24; sisp-1
Gene ID : 64115
mRNA Refseq : NM_022153
Protein Refseq : NP_071436
MIM : 615608
UniProt ID : Q9H7M9

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