Recombinant Human WARS1 Protein (Phe247-Lys458), N-His tagged

• Cat.No.: WARS1-5488H
• Product Overview: Recombinant human WARS1 (Phe247-Lys458) fused with the N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Phe247-Lys458
• Description: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 26.27 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: WARS1 tryptophanyl-tRNA synthetase 1 [ Homo sapiens (human) ]
• Official Symbol: WARS1
• Synonyms: WARS1; tryptophanyl-tRNA synthetase 1; HMN9; WARS; HMND9; IFI53; IFP53; GAMMA-2; NEDMSBA; tryptophan--tRNA ligase, cytoplasmic; epididymis secretory sperm binding protein; hWRS; interferon-induced protein 53; trpRS; tryptophan tRNA ligase 1, cytoplasmic; EC 6.1.1.2
• Gene ID: 7453
• mRNA Refseq: NM_004184
• Protein Refseq: NP_004175
• MIM: 191050
• UniProt ID: P23381