| Description : |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
105.3 kDa |
| AA Sequence : |
MCCTEGSLRKRDSQRAPEAVLCLQL WQRTVPLDTLKGLGTCFPSGPELRG AGIAAAMERASERRTASALFAGFRA LGLFSNDIPHVVRFSALKRRFYVTT CVGKSFHTYDVQKLSLVAVSNSVPQ DICCMAADGRLVFAAYGNVFSAFAR NKEIVHTFKGHKAEIHFLQPFGDHI ISVDTDGILIIWHIYSEEEYLQLTF DKSVFKISAILHPSTYLNKILLGSE QGSLQLWNVKSNKLLYTFPGWKVGV TALQQAPAVDVVAIGLMSGQVIIHN IKFNETLMKFRQDWGPITSISFRTD GHPVMAAGSPCGHIGLWDLEDKKLI NQMRNAHSTAIAGLTFLHREPLLVT NGADNALRIWIFDGPTGEGRLLRFR MGHSAPLTNIRYYGQNGQQILSASQ DGTLQSFSTVHEKFNKSLGHGLINK KRVKRKGLQNTMSVRLPPITKFAAE EARESDWDGIIACHQGKLSCSTWNY QKSTIGAYFLKPKELKKDDITATAV DITSCGNFAVIGLSSGTVDVYNMQS GIHRGSFGKDQAHKGSVRGVAVDGL NQLTVTTGSEGLLKFWNFKNKILIH SVSLSSSPNIMLLHRDSGILGLALD DFSISVLDIETRKIVREFSGHQGQI NDMAFSPDGRWLISAAMDCSIRTWD LPSGCLIDCFLLDSAPLNVSMSPTG DFLATSHVDHLGIYLWSNISLYSVV SLRPLPADYVPSIVMLPGTCQTQDV EVSEETVEPSDELIEYDSPEQLNEQ LVTLSLLPESRWKNLLNLDVIKKKN KPKEPPKVPKSAPFFIPTIPGLVPR YAAPEQNNDPQQSKVVNLGVLAQKS DFCLKLEEGLVNNKYDTALNLLKES GPSGIETELRSLSPDCGGSIEVMQS FLKMIGMMLDRKRDFELAQAYLALF LKLHLKMLPSEPVLLEEITNLSSQV EENWTHLQSLFNQSMCILNYLKSAL LTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
