Active Recombinant Human WNT5B Protein

• Cat.No.: WNT5B-119H
• Product Overview: The mature recombinant human Wnt-5b protein containing 342aa (Gln18-Lys359) without tag was expressed in E. coli.

Specification

• Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.
• Source: E. coli
• Species: Human
• Bio-activity: Measured by its ability to inhibit Wnt-3a-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 125-750 ng/mL.
• Molecular Mass: 38.5 kDa
• Product-Related Proteins: 18-359
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: WNT5B Wnt family member 5B [ Homo sapiens (human) ]
• Official Symbol: WNT5B
• Synonyms: WNT5B; Wnt family member 5B; protein Wnt-5b; Names; WNT-5B protein; wingless-type MMTV integration site family, member 5B
• Gene ID: 81029
• mRNA Refseq: NM_030775
• Protein Refseq: NP_110402
• MIM: 606361
• UniProt ID: Q9H1J7