Recombinant Human YJU2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human YJU2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : YJU2-2654H
Product Overview : CCDC94 MS Standard C13 and N15-labeled recombinant protein (NP_060544) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 37.1 kDa
AA Sequence : MSERKVLNKY YPPDFDPSKI PKLKLPKDRQ YVVRLMAPFN MRCKTCGEYI YKGKKFNARK ETVQNEVYLG LPIFRFYIKC TRCLAEITFK TDPENTDYTM EHGATRNFQA EKLLEEEEKR VQKEREDEEL NNPMKVLENR TKDSKLEMEV LENLQELKDL NQRQAHVDFE AMLRQHRLSE EERRRQQQEE DEQETAALLE EARKRRLLED SDSEDEAAPS PLQPALRPNP TAILDEAPKP KRKVEVWEQS VGSLGSRPPL SRLVVVKKAK ADPDCSNGQP QAAPTPGAPQ NRKEANPTPL TPGASSLSQL GAYLDSDDSN GSNTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : YJU2 YJU2 splicing factor homolog [ Homo sapiens (human) ]
Official Symbol : YJU2
Synonyms : YJU2; YJU2 splicing factor homolog; CCDC94; splicing factor YJU2; coiled-coil domain containing 94; coiled-coil domain-containing protein 94
Gene ID : 55702
mRNA Refseq : NM_018074
Protein Refseq : NP_060544
UniProt ID : Q9BW85

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