Recombinant Human YTHDC2 Protein, GST-tagged

• Cat.No.: YTHDC2-052H
• Product Overview: Recombinant N-terminal GST-tagged human YTHDC2 protein (1288-1421) was purified from E. coli.

Specification

• Description: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
• Source: E. coli
• Species: Human
• Tag: GST
• Molecular Mass: 42.13 kDa
• Protein length: 1288-1421
• Purity: ≥85% estimated by SDS-PAGE
• Stability: ≥ 6 months
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM HEPES, pH 8.0, with 150 mM sodium chloride and 10% glycerol

Gene Information

• Gene Name: YTHDC2 YTH domain containing 2 [ Homo sapiens (human) ]
• Official Symbol: YTHDC2
• Synonyms: YTHDC2; YTH domain containing 2; CAHL; hYTHDC2; 3'-5' RNA helicase YTHDC2; CsA-associated helicase-like protein; probable ATP-dependent RNA helicase YTHDC2; EC 3.6.4.13
• Gene ID: 64848
• mRNA Refseq: NM_022828
• Protein Refseq: NP_073739
• MIM: 616530
• UniProt ID: Q9H6S0