Recombinant human YTHDC2 protein (1288-1421) with a N-terminal GST-tag was expressed in E. coli.
Description :
This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
Source :
E. coli
Species :
Human
Tag :
GST
Form :
50 mM HEPES, pH 8.0, with 150 mM sodium chloride and 10% glycerol
Molecular Mass :
42.13 kDa
Protein length :
1288-1421
Purity :
≥85% estimated by SDS-PAGE
Applications :
WB, ELISA
Stability :
≥ 1 year
Storage :
Store at -80 centigrade
SDS-PAGE of YTHDC2 :
Lane 1: MW Markers, Lane 2: YTHDC2 (2 µg), Lane 3: YTHDC2 (4 µg). Representative gel image shown; actual purity may vary between each batch.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.