Recombinant Human YTHDC2 Protein, GST-tagged

• Cat.No.: YTHDC2-20H
• Product Overview: Recombinant human YTHDC2 protein (1288-1421) with a N-terminal GST-tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1288-1421
• Description: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
• Form: 50 mM HEPES, pH 8.0, with 150 mM sodium chloride and 10% glycerol
• Molecular Mass: 42.13 kDa
• Purity: ≥85% estimated by SDS-PAGE
• Applications: WB, ELISA
• Stability: ≥ 1 year
• Storage: Store at -80 centigrade

Gene Information

• Gene Name: YTHDC2 YTH domain containing 2 [ Homo sapiens (human) ]
• Official Symbol: YTHDC2
• Synonyms: YTHDC2; YTH domain containing 2; CAHL; hYTHDC2; 3'-5' RNA helicase YTHDC2; CsA-associated helicase-like protein; probable ATP-dependent RNA helicase YTHDC2
• Gene ID: 64848
• mRNA Refseq: NM_022828
• Protein Refseq: NP_073739
• MIM: 616530
• UniProt ID: Q9H6S0